Figueroa Damián R, Villagrana Zesati R, Sánchez Fernández L, Benavides Covarrubias E
Ginecol Obstet Mex. 1994 Aug;62:243-8.
It has been described that viral hepatitis is the most frequent cause of jaundice in the pregnant women. In this article we present clinical cases of hepatitis in pregnancy and review the new knowledge about the perinatal repercussion of this association. Hepatitis A is rare in pregnant women and has not a significant perinatal risk. Hepatitis B virus (HBV) can be transmitted from mother to child by transplacental way or at born. Between 40 to 80 per cent of the children infected by this route will develop chronic hepatitis, so the infants of HBsAg carrier mothers must be immunized at birth. The perinatal transmission of hepatitis C virus has been proved but the repercussion in the fetus or newborn is unknown. Hepatitis D virus can only be transmitted from mother to child together with HBV. Hepatitis E has been associated with a mortality from 10 to 40 per cent in pregnant women and with an increase in the preterm pregnancy.
据描述,病毒性肝炎是孕妇黄疸最常见的病因。在本文中,我们展示了妊娠合并肝炎的临床病例,并回顾了有关这种关联的围产期影响的新知识。甲型肝炎在孕妇中罕见,且没有显著的围产期风险。乙型肝炎病毒(HBV)可通过胎盘途径或在分娩时由母亲传播给孩子。通过这种途径感染的儿童中有40%至80%会发展为慢性肝炎,因此HBsAg携带者母亲的婴儿必须在出生时进行免疫接种。丙型肝炎病毒的围产期传播已得到证实,但对胎儿或新生儿的影响尚不清楚。丁型肝炎病毒只能与HBV一起由母亲传播给孩子。戊型肝炎与孕妇10%至40%的死亡率以及早产率增加有关。