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[犬细小病毒:一种病毒病原体起源与发展的最新认识]

[Canine parvovirus: recent knowledge of the origin and development of a viral pathogen].

作者信息

Truyen U

机构信息

Institut für Medizinische Mikrobiologie, Infektions- und Seuchenmedizin, Tierärztliche Fakultät, Ludwig-Maximilians-Universität, München.

出版信息

Tierarztl Prax. 1994 Dec;22(6):579-84.

PMID:7716757
Abstract

Canine parvovirus (CPV) is a "new" virus that suddenly emerged in the mid 1970s. Antigenetically it is very similar to the long known feline panleukopenia virus (FPV). Soon after its appearance CPV was classified as a mutant of FPV. As with all "new" viruses, CPV continues to show active evolution, obvious by the appearance of new antigenic types. Interestingly, the new types, designated CPV-2a and CPV-2b, completely replaced the original type. This review summarizes the facts that are known about the emergence and evolution of CPV and discusses the relevance of the new antigenic types for the diagnosis of CPV and the vaccination against it.

摘要

犬细小病毒(CPV)是一种在20世纪70年代中期突然出现的“新型”病毒。在抗原方面,它与早已为人所知的猫泛白细胞减少症病毒(FPV)非常相似。CPV出现后不久就被归类为FPV的突变体。与所有“新型”病毒一样,CPV继续呈现活跃的进化,新抗原类型的出现就很明显。有趣的是,被命名为CPV-2a和CPV-2b的新类型完全取代了原始类型。这篇综述总结了关于CPV出现和进化的已知事实,并讨论了新抗原类型在CPV诊断和疫苗接种方面的相关性。

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