[前列腺素与分娩发动]

[Prostaglandins and labor onset].

作者信息

Zahradnik H P, Schäfer W, Wetzka B, Breckwoldt M

机构信息

Universitäts-Frauenklinik II Freiburg.

出版信息

Z Geburtshilfe Perinatol. 1994 Oct-Dec;198(5-6):181-5.

PMID:7717005

Abstract

Prostaglandins and lipoxygenase metabolites of arachidonic acid (Eicosanoids) are crucial paracrine regulators of labor. There are many informations about in vitro production and the physiological or pathophysiological role and clinical importance of these substances. However, the all decisive mechanism of the involvement of eicosanoids in birth process is still unknown. In this review we describe the present knowledge about endocrine, paracrine and autocrine regulations of uterine contractions.

摘要

前列腺素和花生四烯酸的脂氧合酶代谢产物（类二十烷酸）是分娩过程中至关重要的旁分泌调节因子。关于这些物质的体外产生、生理或病理生理作用以及临床重要性，已有很多信息。然而，类二十烷酸参与分娩过程的关键机制仍不清楚。在本综述中，我们描述了目前关于子宫收缩的内分泌、旁分泌和自分泌调节的知识。