Razis P A, Robinson D L, Alberry R
St George's Hospital, Tooting, London.
Br J Anaesth. 1995 Mar;74(3):335-7. doi: 10.1093/bja/74.3.335.
We present two patients who became unrousable within 48h after general anaesthesia for non-neurosurgical operations; both were found to have frontal meningiomas. Analysis of these and previous reports suggest that several anaesthetic and perioperative factors probably combine to contribute to the accelerated presentation of these previously "silent" tumours, and we recommend that dexamethasone should be administered early in the course of unexplained neurological deterioration after operation.
我们报告了两名患者,他们在接受非神经外科手术的全身麻醉后48小时内变得无法唤醒;两人均被发现患有额叶脑膜瘤。对这些病例以及既往报告的分析表明,多种麻醉和围手术期因素可能共同作用,促使这些先前“无症状”的肿瘤加速显现,我们建议在术后出现无法解释的神经功能恶化时应尽早给予地塞米松。