Chapman A M, Debski E A
School of Biological Sciences, University of Kentucky, Lexington.
Vis Neurosci. 1995 Jan-Feb;12(1):1-9. doi: 10.1017/s0952523800007264.
Using rhodamine-labelled latex beads as a retrograde tracer, we have shown that a subset of the neurons projecting from the lateral thalamic nucleus to the optic tectum of the leopard frog are neuropeptide Y-like immunoreactive (NPY-IR). In juvenile frogs, approximately twice as many lateral thalamic nucleus cells from this area project to the ipsilateral tectum as project to the contralateral tectum. NPY-IR cells make up 25% of the projection to the ipsilateral tectum and 13% of the projection to the contralateral tectum. The ipsilateral NPY-IR projection from the lateral nucleus was present in tadpoles and was similar in its characteristics to that found in the juvenile frog. However, the contralateral tectal projection was virtually nonexistent in these animals. The results of these experiments suggest that NPY from the lateral nucleus is released into the ipsilateral tectal neuropil in both the developing and adult frog.
使用罗丹明标记的乳胶珠作为逆行示踪剂，我们已经表明，从豹蛙外侧丘脑核投射到视顶盖的一部分神经元是神经肽Y样免疫反应性（NPY-IR）的。在幼蛙中，来自该区域的外侧丘脑核细胞投射到同侧顶盖的数量大约是投射到对侧顶盖的两倍。NPY-IR细胞占投射到同侧顶盖的25%，占投射到对侧顶盖的13%。外侧核的同侧NPY-IR投射在蝌蚪中就已存在，其特征与在幼蛙中发现的相似。然而，在这些动物中，对侧顶盖投射实际上不存在。这些实验结果表明，在发育中的和成体青蛙中，来自外侧核的NPY都释放到同侧顶盖神经毡中。
