Nomura T, Lebowitz L, Koide Y, Keehn L, Oka Y
Department of Anesthesiology, Albert Einstein College of Medicine/Montefiore Medical Center, Bronx, NY 10461, USA.
J Cardiothorac Vasc Anesth. 1995 Feb;9(1):9-17. doi: 10.1016/s1053-0770(05)80049-7.
Hepatic venous flows (HVFs) were evaluated to assess right-heart function by transesophageal Doppler echocardiography in 45 patients undergoing coronary artery bypass graft (CABG) surgery. Peak velocity and time velocity integral of A-wave (reverse flow in end diastole), S-wave (forward flow in systole), V-wave (reverse flow in late systole), and D-wave (forward flow in diastole) of biphasic HVF were examined. Peak systolic-diastolic ratio (S/D) of biphasic HVF and reverse flow ratio (% reversal flow/forward flow [RF/FF]) of both biphasic and monophasic HVF also were examined. Tricuspid regurgitation (TR) was assessed by color Doppler image. All data were obtained after performing the following: induction of anesthesia (stage 1); pericardiectomy (stage 2); cardiopulmonary bypass (CPB) (stage 3); and closure of sternum (stage 4). HVFs at stage 1 were obtained in all 45 patients, and the peak S/D in patients with a history of inferior wall myocardial infarction (MI) was significantly less than that in patients without a history of MI (p < 0.05). HVFs of 35 patients were recorded successfully at all stages. In 5 of these 35 patients, HVF patterns became monophasic after CPB, and only one of those patients had severe TR. In the rest of the 30 patients with biphasic patterns throughout the operation, peak A and D velocities increased (p < 0.01), whereas peak S and V velocities decreased (p < 0.01) after CPB compared with those before CPB. Consequently, peak S/D was reduced (p < 0.01), and %RF/FF increased (p < 0.05). These post-CPB changes were associated with increased (p < 0.01) pulmonary artery diastolic and right atrial pressures.(ABSTRACT TRUNCATED AT 250 WORDS)
通过经食管多普勒超声心动图评估45例行冠状动脉旁路移植术(CABG)患者的肝静脉血流(HVF),以评估右心功能。检测双相HVF的A波(舒张末期反流)、S波(收缩期正向血流)、V波(收缩末期反流)和D波(舒张期正向血流)的峰值速度和时间速度积分。还检测双相HVF的收缩期-舒张期峰值比(S/D)以及双相和单相HVF的反流比(反流血流百分比/正向血流百分比[RF/FF])。通过彩色多普勒图像评估三尖瓣反流(TR)。所有数据均在进行以下操作后获得:麻醉诱导(第1阶段);心包切除术(第2阶段);体外循环(CPB)(第3阶段);胸骨闭合(第4阶段)。45例患者均在第1阶段获得HVF数据,下壁心肌梗死(MI)病史患者的峰值S/D显著低于无MI病史患者(p<0.05)。35例患者在所有阶段均成功记录HVF。在这35例患者中,5例在CPB后HVF模式变为单相,其中只有1例有严重TR。在其余30例手术全程为双相模式的患者中,与CPB前相比,CPB后A波和D波峰值速度增加(p<0.01),而S波和V波峰值速度降低(p<0.01)。因此,峰值S/D降低(p<0.01),%RF/FF增加(p<0.05)。这些CPB后的变化与肺动脉舒张压和右心房压力升高(p<0.01)相关。(摘要截断于250字)