Suganuma H, Yoshimi T, Kita T, Okano H, Suzuki Y, Oki Y, Chida K, Sato A
Department of Internal Medicine, Hamamatsu University School of Medicine.
Intern Med. 1994 Dec;33(12):795-8. doi: 10.2169/internalmedicine.33.795.
An unusual case with metastatic spread of a small oat cell lung carcinoma to the hypothalamo-pituitary region and pineal body presenting as pituitary insufficiency is reported. Computed tomographic scan revealed an isodense mass in the hypothalamo-pituitary region and pineal body that was strongly enhanced by contrast medium. Magnetic resonance imaging demonstrated a downward displacement of the posterior lobe of the pituitary by the hypothalamo-pituitary mass. Dynamic assessment of hypothalamo-pituitary function showed hypopituitarism and diabetes insipidus; partial recovery was observed with the improvement in the carcinoma by chemotherapy. The brain was subsequently irradiated. The patient survived 10 months.
报告了一例罕见病例，小细胞肺癌转移至下丘脑 - 垂体区域和松果体，表现为垂体功能减退。计算机断层扫描显示下丘脑 - 垂体区域和松果体有等密度肿块，造影剂增强明显。磁共振成像显示下丘脑 - 垂体肿块使垂体后叶向下移位。下丘脑 - 垂体功能的动态评估显示垂体功能减退和尿崩症；化疗使癌症病情改善后观察到部分恢复。随后对脑部进行了放疗。患者存活了10个月。
