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[哮喘早期和晚期反应期间的粒细胞化学发光]

[Granulocyte chemiluminescence during early and late asthmatic reaction].

作者信息

Medrala W, Małolepszy J, Wolańczyk-Medrala A, Wrzyszcz M, Liebhart E, Kraus-Filarska M

机构信息

Katedry i Kliniki Chorób Wewnetrznych i Alergologii, Akademii Medycznej we Wrocławiu.

出版信息

Pneumonol Alergol Pol. 1994;62(11-12):594-8.

PMID:7719258
Abstract

Allergic asthmatic patients were challenged with specific allergen resulting in early and dual asthmatic reaction. FMLP induced granulocyte chemiluminescence was measured before and in 10 min, 60 min, 4 hours and 24 hours after allergen challenge. We have observed significant decrease of granulocyte chemiluminescence in both groups. In patient with early asthmatic reaction decrease of luminescence was observed during first hour only. In patients with dual asthmatic reaction decrease of luminescence was observed during 24 hours after allergen challenge.

摘要

对过敏性哮喘患者进行特异性变应原激发试验,引发早期和双重哮喘反应。在变应原激发试验前以及激发后10分钟、60分钟、4小时和24小时测量FMLP诱导的粒细胞化学发光。我们观察到两组患者的粒细胞化学发光均显著降低。在早期哮喘反应患者中,仅在第1小时观察到发光降低。在双重哮喘反应患者中,在变应原激发试验后24小时内观察到发光降低。

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Pneumonol Alergol Pol. 1994;62(11-12):594-8.
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