胆碱和乙醇胺对四膜虫中肌醇磷脂（PI）系统合成与分解的影响。
Effects of choline and ethanolamine on the synthesis and breakdown of the inositol phospholipid (PI) system in Tetrahymena.
作者信息
Kovács P, Csaba G
机构信息
Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.
出版信息
Cell Biochem Funct. 1995 Mar;13(1):61-7. doi: 10.1002/cbf.290130111.
Lower concentrations of choline chloride and ethanolamine (10(-3) M; 10(-5) M) increased phosphatidyl inositol (PI), phosphatidyl inositol monophosphate (PIP) and phosphatidyl inositol bisphosphate (PIP2) level of Tetrahymena, while higher concentrations (10(-2) M) decreased them. These two substances also influenced, however in a less obvious way, the transformation of inositol phospholipids. The experiments draw attention to the sensitivity of the precursors of the second messenger system at a phylogenetically low level.
较低浓度的氯化胆碱和乙醇胺（10⁻³ M；10⁻⁵ M）可提高四膜虫的磷脂酰肌醇（PI）、磷脂酰肌醇单磷酸（PIP）和磷脂酰肌醇二磷酸（PIP2）水平，而较高浓度（10⁻² M）则使其降低。然而，这两种物质对肌醇磷脂的转化也有影响，不过不太明显。这些实验凸显了第二信使系统前体在系统发育较低水平时的敏感性。
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