Xu S M, Peng S Y, Chen P H
Second Affiliated Hospital, Zhejian Medical University, Hangzhou.
Zhonghua Wai Ke Za Zhi. 1994 Sep;32(9):565-7.
This paper reports one case with glucagonoma syndrome that resection of the primary glucagonoma in the pancreas was done. There was metastasis one in liver and lymph node. The definitive diagnosis was established by immunohistochemical analysis. The patient by immunohistochemical analysis. The patient remained well for 27 months and gained 5 kg of weight. Another experiences of diagnosis and treatment of 8 cases of malignant glucagonoma collected in chinese literature were reviewed. The clinical specialty of glucagonoma syndrome. diagnosis and management were discussed suggesting two points: on diagnosis the clinical specialty is a important clues: palliative primary tumor resection may be significant clinical improvement and prolonged survival.
本文报告1例胰高血糖素瘤综合征患者,该患者接受了胰腺原发性高血糖素瘤切除术,存在肝和淋巴结转移。通过免疫组化分析确诊。经免疫组化分析,该患者状况良好达27个月,体重增加了5千克。回顾了中国文献中收集的另外8例恶性高血糖素瘤的诊治经验。讨论了高血糖素瘤综合征的临床特点、诊断及治疗,提出两点:在诊断方面,临床特点是重要线索;姑息性切除原发性肿瘤可能显著改善临床症状并延长生存期。