Chen J H, Wei G Q, Chen M Y
Department of Thoracic Surgery, Henan Cancer Hospital, Zheng Zhou.
Zhonghua Zhong Liu Za Zhi. 1994 Nov;16(6):441-3.
The authors studied retrospectively lymph node metastatic status impacts on survival of the 212 patients with thoracic esophageal squamous cell carcinoma and lymph node metastasis after curative resection. 663 (19.4%) of the total 3419 lymph nodes examined (an average of 16.1 per patient) were proved to be positive. The overall 5-year survival rate was 19.3%. The results showed that no difference in survival was observed in relation to the site of the involved lymph node. Difference in survival based on the number of metastatic lymph nodes (1 or > or = 2) and the frequency of positive nodes (< or = 10% or > 10%). The results indicate that staging of esophageal cancer should be made according to the absolute number and the relative frequency of lymph nodes involved. The effectiveness and limitation of extended lymph node dissection in relation to prognosis was discussed.
作者回顾性研究了212例胸段食管鳞状细胞癌患者根治性切除术后淋巴结转移状态对生存的影响。在总共检查的3419个淋巴结(平均每位患者16.1个)中,有663个(19.4%)被证实为阳性。总体5年生存率为19.3%。结果显示,受累淋巴结部位与生存率无差异。基于转移淋巴结数量(1个或≥2个)和阳性淋巴结频率(≤10%或>10%)的生存率存在差异。结果表明,食管癌分期应根据受累淋巴结的绝对数量和相对频率来确定。讨论了扩大淋巴结清扫术对预后的有效性和局限性。