Tikhonova T V, Gladysheva I P, Larionova N I
Department of Chemistry, M.V. Lomonosov Moscow State University, Russian Federation.
FEBS Lett. 1995 Apr 3;362(2):225-8. doi: 10.1016/0014-5793(95)00202-k.
The classical Bowman-Birk inhibitor from soya retards strongly the hydrolysis of elastin catalyzed by leukocyte elastase, cathepsin G and a mixture of both. The inhibitory effect is practically unaffected by both the adsorption of the enzymes on elastin and prolongation of the enzymatic reaction.