Janse A J, van Coevorden F, Peterse H, Keus R B, van Dongen J A
Department of Surgery, The Netherlands Cancer Institute/Antoni van Leeuwenhoek ziekenhuis, Amsterdam.
Eur J Surg Oncol. 1995 Apr;21(2):155-8. doi: 10.1016/s0748-7983(95)90270-8.
A series of eight patients with chronic lymphedema-related lymphangiosarcoma is presented. All but one case showed a typical rapid progression and fatal outcome, as has been reported in other series. In one patient the lymphangiosarcoma developed on the chest wall, the axilla and the arm where persisting lymphedema and fibrosis occurred after bilateral mastectomy and bilateral postoperative radiotherapy. In this patient an asymptomatic course and slow locoregional progression of lesions was seen. The clinical picture, the etiological considerations and the therapeutic options of the lymphedema-induced lymphangiosarcoma with regard to the literature are discussed.
本文报告了8例与慢性淋巴水肿相关的淋巴管肉瘤患者。除1例病例外，其他所有病例均表现出典型的快速进展和致命结局，正如其他系列报道中所述。1例患者的淋巴管肉瘤发生于胸壁、腋窝和手臂，该部位在双侧乳房切除术后及双侧术后放疗后出现持续性淋巴水肿和纤维化。在该患者中，病变呈无症状病程且局部进展缓慢。结合文献讨论了淋巴水肿诱发的淋巴管肉瘤的临床表现、病因学考量及治疗选择。
