Audan A, Bruley Des Varannes S, Georgelin T, Sagan C, Cloarec D, Serraz H, Le Bodic L
Clinique des Maladies de l'Appareil Digestif, Hôpital Guillaume-et-René-Laennec, Nantes.
Gastroenterol Clin Biol. 1995 Jan;19(1):123-6.
We report the association of primary sclerosing cholangitis and systemic lupus erythematosus in a 39 year-old man. Six months after a diagnosis of primary sclerosing cholangitis was established, the patient was hospitalized for a pleural effusion and acute pericarditis. Emergency pericardiocentesis, was required due to sudden cardiac tamponnade. Plasmatic anti-DNA and anti-nuclear antibodies were present. Treatment by steroids greatly improved symptoms. This clinical association suggests that some immune disorders may be common to the two diseases.
我们报告了一名39岁男性原发性硬化性胆管炎与系统性红斑狼疮的关联。在原发性硬化性胆管炎确诊6个月后，该患者因胸腔积液和急性心包炎住院。由于突发心脏压塞，需要进行紧急心包穿刺术。血浆中存在抗DNA和抗核抗体。类固醇治疗使症状大大改善。这种临床关联表明，某些免疫紊乱可能是这两种疾病共有的。
