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Benzpyrene treatment in adulthood increases the testosterone level in neonatally steroid(allylestrenol)-treated male rats.

作者信息

Pap E, Csaba G

机构信息

Department of Biology, Semmelweis University of Medicine, Budapest, Hungary.

出版信息

Gen Pharmacol. 1994 Dec;25(8):1699-701. doi: 10.1016/0306-3623(94)90374-3.

Abstract
  1. Serum testosterone level was significantly elevated in adult male rats after a single perinatal allylestrenol administration. 2. Benzpyrene treatment of adult rats perinatally treated with allylestrenol, did not cause changes 1 week after benzpyrene treatment, but 3 weeks later an extremely high serum testosterone level was found. 3. In control animals benzpyrene administration in adulthood did not influence the serum testosterone level either 1 or 3 weeks following the treatment.
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