Stock R G, Stone N N, Wesson M F, DeWyngaert J K
Department of Radiation Oncology, Mount Sinai School of Medicine, New York, NY 10029, USA.
Int J Radiat Oncol Biol Phys. 1995 Apr 30;32(1):219-25. doi: 10.1016/0360-3016(95)00521-Y.
Ultrasound-guided transperineal prostate implantation is a new technique for performing permanent isotope implants of the prostate. The details of the technique are presented to demonstrate its ability to place radioactive seeds three-dimensionally within the prostate gland to achieve uniform dose distribution without the need for complicated preplanning.
An accurate measurement of the prostate volume is made using biplanar transrectal ultrasound. The total activity to be implanted is derived from a look-up table based on prostate volume. The basic plan is to implant 60-70% of the total activity in the periphery of the gland and the remaining activity in the interior of the gland. The ultrasound transducer provides visualization of the prostate through transverse, longitudinal and oblique cuts and allows for accurate placement of implant needles, approximately 1 cm apart. In addition, these needles can be moved through the prostate under constant visualization, thus allowing for precise seed placement.
The setup of the transrectal ultrasound device as well as prostate volume measurements are performed in 10 to 15 min. The actual placement of the needles and seed implantation takes 1 to 1.5 h to perform. Postimplantation dosimetric evaluation is performed using orthogonal x-ray films and 3 mm thick CT slices taken at 3 mm intervals. This evaluation has confirmed accurate seed placement within the prostate gland.
Interactive ultrasound guided transperineal prostate implantation is a fast and accurate method of performing permanent radioactive isotope prostate implants.
超声引导下经会阴前列腺植入术是一种用于进行前列腺永久性同位素植入的新技术。现将该技术的细节予以介绍，以展示其在前列腺腺体内三维放置放射性粒子以实现均匀剂量分布而无需复杂术前规划的能力。
使用双平面经直肠超声准确测量前列腺体积。根据前列腺体积从查阅表得出要植入的总活度。基本方案是将总活度的60%至70%植入腺体周边，其余活度植入腺体内。超声换能器通过横向、纵向和斜向切面提供前列腺的可视化图像，并允许精确放置植入针，针距约为1厘米。此外，这些针可在持续可视化的情况下在前列腺内移动，从而实现精确的粒子放置。
经直肠超声设备的设置以及前列腺体积测量在10至15分钟内完成。针的实际放置和粒子植入需要1至1.5小时。植入后剂量学评估使用正交X线片和间隔3毫米拍摄的3毫米厚CT切片进行。该评估已证实粒子在前列腺腺体内放置准确。
交互式超声引导下经会阴前列腺植入术是一种快速、准确的进行永久性放射性同位素前列腺植入的方法。
