Schoysman R, Vanderzwalmen P, Nijs M, Segal L, Segal-Bertin G, Geerts L, van Roosendaal E, Schoysman-Deboeck A
Schoysman Infertility Management Foundation, I.V.F. Laboratory, Vilvoorde, Belgium.
J Androl. 1994 Nov-Dec;15 Suppl:10S-13S.
The fertilizing capacity of human testicular spermatozoa and the positive outcome of an in vitro fertilization program open a wide range of opportunities for men suffering from obstructive and inoperable azoospermia. In six cases, subzonal sperm injection or intracytoplasmic sperm injection techniques were applied to inject testicular spermatozoa into human oocytes. The fertilization rate after testicular sperm injection reached 45%. Normal cleavage was observed and replacement of 10 embryos in 6 patients resulted in one chemical and one ongoing pregnancy.
人类睾丸精子的受精能力以及体外受精程序的积极成果为患有梗阻性和无法手术的无精子症的男性带来了广泛的机会。在6例病例中，采用了透明带下精子注射或卵胞浆内单精子注射技术将睾丸精子注入人类卵母细胞。睾丸精子注射后的受精率达到45%。观察到正常分裂，6例患者植入10个胚胎，结果有1例发生生化妊娠，1例持续妊娠。
