Tamada Y, Yokochi K, Nitta Y, Ikeya T, Hara K, Owaribe K
Department of Dermatology, Aichi Medical University, Japan.
J Am Acad Dermatol. 1995 May;32(5 Pt 2):883-7. doi: 10.1016/0190-9622(95)91554-0.
We describe a man with lichen planus pemphigoides. Direct immunofluorescence studies of peribullous skin showed linear deposition of IgG and C3 in the basement membrane zone. Indirect immunofluorescence studies disclosed circulating anti-basement membrane zone antibodies. Immunoelectron microscopy demonstrated binding of antibodies to the hemidesmosomes and lamina lucida. The patient's serum defined only the minor bullous pemphigoid antigen with a molecular weight of 180 kd. These findings suggest the coexistence of lichen planus and bullous pemphigoid in lichen planus pemphigoides.
我们描述了一名患有扁平苔藓类天疱疮的男性患者。对水疱周围皮肤进行的直接免疫荧光研究显示，IgG和C3在基底膜带呈线性沉积。间接免疫荧光研究揭示了循环抗基底膜带抗体的存在。免疫电子显微镜显示抗体与半桥粒和透明板结合。患者血清仅识别出分子量为180kd的次要类天疱疮抗原。这些发现提示在扁平苔藓类天疱疮中扁平苔藓和类天疱疮共存。
