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人类免疫缺陷病毒血清学状态的知晓情况对避孕选择和再次妊娠的影响。

The impact of knowledge of human immunodeficiency virus serostatus on contraceptive choice and repeat pregnancy.

作者信息

Lindsay M K, Grant J, Peterson H B, Willis S, Nelson P, Klein L

机构信息

Department of Obstetrics and Gynecology, Emory University, Atlanta, USA.

出版信息

Obstet Gynecol. 1995 May;85(5 Pt 1):675-9. doi: 10.1016/0029-7844(95)00018-m.

Abstract

OBJECTIVE

To examine relationships among human immunodeficiency virus (HIV) serostatus, postpartum contraceptive choice, and the rate of repeat pregnancy within a short interval.

METHODS

This retrospective cohort study was performed in 83 seropositive and 218 seronegative women identified from an inner-city prenatal population undergoing routine voluntary HIV antibody screening from July 1987 through June 1989. Postpartum contraceptive choices and rate of repeat pregnancies were compared based on HIV serostatus.

RESULTS

Seropositive women were significantly more likely than seronegative women to undergo tubal sterilization (27 versus 15%; odds ratio [OR] 2.9, 95% confidence interval [CI] 1.5-5.9). This relationship persisted after controlling for age, race, marital status, and parity by logistic regression modeling (adjusted OR 2.9, 95% CI 1.4-5.9). Seropositive women were significantly less likely than seronegative women to select oral contraceptives (34 versus 68%; OR 0.2, 95% CI 0.1-0.4), a relationship that persisted after controlling for age, race, marital status, parity, and foam and condom use (adjusted OR 0.2, 95% CI 0.1-0.5). Seropositive women were significantly more likely than seronegative women to select foam and condoms as their primary method of contraception (30 versus 15%; OR 2.4, 95% CI 1.2-4.5), a relationship that did not persist after controlling for age, race, marital status, and parity (adjusted OR 0.7, 95% CI 0.4-1.3). The risk of repeat pregnancy was slightly lower in seropositive versus seronegative women (34 versus 44%; OR 0.7, 95% CI 0.4-1.3). Most repeat pregnancies among seropositive and seronegative women were unplanned (90 and 82%, respectively).

CONCLUSION

There was a relationship between the method of postpartum contraception and HIV serostatus, but no significant difference in repeat pregnancy rates associated with choice of method.

摘要

目的

研究人类免疫缺陷病毒(HIV)血清学状态、产后避孕方式选择以及短时间内再次妊娠率之间的关系。

方法

本回顾性队列研究纳入了1987年7月至1989年6月在市中心接受常规自愿HIV抗体筛查的产前人群中识别出的83名血清学阳性和218名血清学阴性女性。根据HIV血清学状态比较产后避孕方式选择和再次妊娠率。

结果

血清学阳性女性比血清学阴性女性更有可能接受输卵管绝育术(27%对15%;优势比[OR]2.9,95%置信区间[CI]1.5 - 5.9)。通过逻辑回归模型控制年龄、种族、婚姻状况和产次后,这种关系仍然存在(调整后OR 2.9,95% CI 1.4 - 5.9)。血清学阳性女性比血清学阴性女性选择口服避孕药的可能性显著更低(34%对68%;OR 0.2,95% CI 0.1 - 0.4),在控制年龄、种族、婚姻状况、产次以及泡沫剂和避孕套使用情况后,这种关系仍然存在(调整后OR 0.2,95% CI 0.1 - 0.5)。血清学阳性女性比血清学阴性女性更有可能选择泡沫剂和避孕套作为主要避孕方法(30%对15%;OR 2.4,95% CI 1.2 - 4.5),在控制年龄、种族、婚姻状况和产次后,这种关系不再存在(调整后OR 0.7,95% CI 0.4 - 1.3)。血清学阳性女性再次妊娠的风险略低于血清学阴性女性(34%对44%;OR 0.7,95% CI 0.4 - 1.3)。血清学阳性和血清学阴性女性中的大多数再次妊娠都是意外妊娠(分别为90%和82%)。

结论

产后避孕方式与HIV血清学状态之间存在关系,但与避孕方式选择相关的再次妊娠率没有显著差异。

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