Brewer J E, Tvedt M A, Adams T P, Kroll M W
Angeion Corporation, Plymouth, Minnesota 55447.
Pacing Clin Electrophysiol. 1995 Jan;18(1 Pt 2):214. doi: 10.1111/j.1540-8159.1995.tb02507.x.
Typically, an implantable cardioverter defibrillator (ICD) uses a cardioversion shock that is a lower voltage pulse of the same morphology and tilt as its defibrillation pulse. We investigated the internal electric field resulting from an ICD low voltage shock to determine whether its field characteristics matched those of the internal electric field of a high voltage shock. We attached epicardial patch electrodes, for shock delivery, to five fresh pig hearts placed in a diluted, heparinized saline bath. We inserted two plunge electrodes into the myocardium to measure an internal voltage proportional to the electric field. Monophasic 20-msec shocks, from a 140-microF capacitor, ranging from 0.1-30 joules, were delivered through the patches. We measured the current, external voltage, and internal voltage every 0.1 msec throughout the duration of a shock. For each shock, we calculated the time point that represented the 65% tilt position as measured across the patch electrodes. At this 65% tilt time position, we measured the pulse widths and calculated the internal tilt from the internal voltage. We found that the initial internal voltage for the 30-joule shock was 173 +/- 40 volts compared to 10 +/- 2 volts for the 0.1-joule shock. Similarly, we found that the final internal voltage for the 30-joule shock was 56 +/- 14 volts compared to 2 +/- 1 volts for the 0.1-joule shock. Thus, the internal tilt for the 30-joule shock was 68 +/- 1% versus 82 +/- 3% for the 0.1-joule shock (P < 0.05).(ABSTRACT TRUNCATED AT 250 WORDS)
通常,植入式心脏复律除颤器(ICD)使用的心脏复律电击是一种与除颤脉冲形态和倾斜度相同的较低电压脉冲。我们研究了ICD低电压电击产生的内部电场,以确定其场特征是否与高电压电击的内部电场特征相匹配。我们将用于电击传递的心外膜贴片电极附着在放置于稀释的肝素化盐浴中的五个新鲜猪心脏上。我们将两个插入式电极插入心肌中,以测量与电场成比例的内部电压。通过贴片传递来自140微法电容器的单相20毫秒电击,能量范围为0.1 - 30焦耳。在电击持续期间,我们每0.1毫秒测量一次电流、外部电压和内部电压。对于每次电击,我们计算代表跨贴片电极测量的65%倾斜位置的时间点。在这个65%倾斜时间位置,我们测量脉冲宽度并根据内部电压计算内部倾斜度。我们发现,30焦耳电击的初始内部电压为173±40伏,而0.1焦耳电击的初始内部电压为10±2伏。同样,我们发现30焦耳电击的最终内部电压为56±14伏,而0.1焦耳电击的最终内部电压为2±1伏。因此,30焦耳电击的内部倾斜度为68±1%,而0.1焦耳电击的内部倾斜度为82±3%(P<0.05)。(摘要截断于250字)