Bernheim J, Touraine J L, David L, Faivre J M, Traeger J
Nephron. 1976;16(5):381-7. doi: 10.1159/000180623.
Parathormone levels were determined in 17 patients with functioning renal transplants. In 8 patients recently transplanted, very high serum levels of parathormone were found without obvious relation to the glomerular filtration rate. Hypophosphatemia was also present in these cases. In 9 other patients studied 2-7 years after transplantation the mean level of parathormone was lower than in the previous group but levels above normal were noted in half of the patients, some of which had perfect renal function and normal serum phosphorus. The response to induced hypercalcemia was used as a sensitive test to reveal abnormal responses even in cases which initially had normal peripheral levels of parathormone. From these results, tertiary hyperparathyroidism would appear to be rare although hyperfunctioning parathyroid glands can be demonstrated long after kidney transplantation, even when renal function is close to normal.
对17例有功能的肾移植患者测定了甲状旁腺激素水平。在8例近期接受移植的患者中，发现血清甲状旁腺激素水平非常高，且与肾小球滤过率无明显关系。这些病例中也存在低磷血症。在移植后2至7年研究的其他9例患者中，甲状旁腺激素的平均水平低于前一组，但一半的患者甲状旁腺激素水平高于正常，其中一些患者肾功能良好且血清磷正常。即使在最初外周甲状旁腺激素水平正常的病例中，诱导性高钙血症反应也被用作一项敏感试验，以揭示异常反应。从这些结果来看，尽管在肾移植后很长时间，即使肾功能接近正常时，也可证明甲状旁腺功能亢进，但三发性甲状旁腺功能亢进似乎很少见。
