双二氧代哌嗪丙烷（ICRF 159；NSC 129,943）用于急性白血病的临床试验。
Clinical trials with bis-dioxopiperazine propane (ICRF 159; NSC 129, 943) in acute leukaemias.
作者信息
Krepler P, Pawlowsky J
出版信息
Osterr Z Onkol. 1975;2(4):112-4.
PMID:772517
Abstract
Clinical experience is reported with bis-dioxopiperazine propane (ICRF 159) in 20 children with acute leukaemia in relapse. They were resistant to most of the generally used cytotoxic drugs. Despite the unfavourable selection of cases, two complete and seven incomplete remissions lasting from 1 to 6 months were obtained.
摘要
报告了双二氧代哌嗪丙烷（ICRF 159）治疗20例急性白血病复发患儿的临床经验。这些患儿对大多数常用的细胞毒性药物耐药。尽管病例选择不佳，但仍获得了2例完全缓解和7例不完全缓解，缓解期持续1至6个月。
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