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[人降钙素的循环形式]

[The circulating forms of human calcitonin].

作者信息

Heynen G, Franchimont P

出版信息

Pathol Biol (Paris). 1975 Dec;23(10):815-9.

PMID:772525
Abstract

It is demonstrated for the first time that there are at least two forms of immunoreactive CT in serum: the first has the same physico-chemical properties as synthetic CT whereas the second one has a higher molecular weight than synthetic CT, close to the molecular weight of serum albumin. Such heterogeneity was found in the sera of normal subjects and in the sera of patients suffering from several diseases. Results suggest that the percentages of these two forms vary from one serum to another.

摘要

首次证明血清中至少存在两种免疫反应性降钙素形式

第一种具有与合成降钙素相同的物理化学性质,而第二种分子量高于合成降钙素,接近血清白蛋白的分子量。在正常受试者的血清和患有几种疾病的患者的血清中均发现了这种异质性。结果表明,这两种形式的百分比因血清而异。

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