Akmayev I G, Fidelina O V, Vikhreva O V
Institute of Experimental Endocrinology, Moscow, Russia.
Acta Biol Hung. 1994;45(2-4):143-53.
Using the stereological, histochemical and electron microscopic approaches the cellular and synaptic structure of the rat dorsal vagal nucleus (DVN) were studied. Cellular organization of the DVN does not allow to distinguish any separate subnuclei but a conspicuous population of mainly small neurons in rostral extension of its lateral part lacking AChE activity. DVN neurons with high and moderate AChE activities are manifest on the 5th postnatal day. Their number increases on the 7th day. In this critical period of the brain sexual differentiation, a sexual dimorphism was observed in the activity of DVN cholinergic neurons. The electron microscopic studies showed a wide variety of the DVN synaptic patterns. In the rat DVN were found complicated synaptic structures resembling glomeruli. Two types of synaptic glomeruli are distinguished. The results suggest that DVN can be regarded as a sex-dependent brain area involved in a high level of information processing.
运用体视学、组织化学和电子显微镜方法，对大鼠迷走神经背核（DVN）的细胞和突触结构进行了研究。DVN的细胞组织无法区分出任何独立的亚核，但在其外侧部分的吻侧延伸区域有一群明显的主要为小神经元，缺乏乙酰胆碱酯酶（AChE）活性。具有高和中度AChE活性的DVN神经元在出生后第5天出现。其数量在第7天增加。在这个脑性分化的关键时期，观察到DVN胆碱能神经元的活性存在性二态性。电子显微镜研究显示了DVN突触模式的多样性。在大鼠DVN中发现了类似肾小球的复杂突触结构。区分出两种类型的突触小球。结果表明，DVN可被视为一个参与高水平信息处理的性别依赖性脑区。
