Krishnan K R, Hays J C, Tupler L A, George L K, Blazer D G
Department of Psychiatry, Duke University Medical Center, Durham, NC 27710, USA.
Am J Psychiatry. 1995 May;152(5):785-8. doi: 10.1176/ajp.152.5.785.
The authors examined the relationship between age at onset of first depressive episode and clinical features in elderly depressed patients.
They used data on age at onset and clinical features in 246 elderly depressed patients treated at the National Institute of Mental Health Clinical Research Center for the Study of Depression in Later Life, located at Duke University.
Two variables--loss of interest and number of depressive episodes--were related to age at onset in all analyses.
This study confirms the hypothesis that apathy is more prominent in late-onset than in early-onset depression.
作者研究了老年抑郁症患者首次抑郁发作的发病年龄与临床特征之间的关系。
他们使用了位于杜克大学的美国国立精神卫生研究所晚年抑郁症临床研究中心治疗的246名老年抑郁症患者的发病年龄和临床特征数据。
在所有分析中,兴趣丧失和抑郁发作次数这两个变量与发病年龄有关。
本研究证实了晚发性抑郁症比早发性抑郁症中冷漠更为突出这一假设。