Borovik A S, Frank-Kamenetskii M D
Institute of Molecular Genetics, Russian Academy of Sciences, Moscow.
J Biomol Struct Dyn. 1994 Dec;12(3):655-69. doi: 10.1080/07391102.1994.10508765.
By performing several statistical tests, we confirm that long-range correlations exist and are typical for long eukaryotic DNA sequences. Different types of "critical exponents" for characterization of DNA fractality are discussed. As to possible explanation of the phenomenon, our computer simulations indicate that simple mosaic structure of genome, without correlations between blocks, cannot be solely accounted for the observed statistical properties of DNA texts. We propose the concept of "fractal patchiness", which fully explains statistical observations, and shed light on the possible origin of long-range correlations in DNA sequences.
通过进行多项统计测试，我们证实长程相关性确实存在，并且是真核生物长DNA序列的典型特征。文中讨论了用于表征DNA分形性的不同类型的“临界指数”。关于该现象的可能解释，我们的计算机模拟表明，基因组的简单镶嵌结构（各片段之间无相关性）无法完全解释所观察到的DNA文本的统计特性。我们提出了“分形斑块性”的概念，它能充分解释统计观测结果，并揭示了DNA序列中长程相关性的可能起源。
