Laurenzo J F, Canady J W, Zimmerman M B, Smith R J
Department of Otolaryngology, University of Iowa Hospitals and Clinics, Iowa City, USA.
Arch Otolaryngol Head Neck Surg. 1995 May;121(5):556-61. doi: 10.1001/archotol.1995.01890050048009.
To examine the effects of soft-tissue manipulation, rigid microplate fixation, and multiple osteotomies on the growing midface in rabbits.
Randomized, controlled experiment.
Forty 6-week-old male New Zealand white rabbits.
Group 1, exposure of the left nasofrontal and midzygomatic arch regions with periosteal elevation; group 2, osteotomies at left nasofrontal suture and midzygomatic arch; group 3, rigid plate fixation of osteotomies; and group 4, rigid plate fixation alone. Animals were killed at age 20 weeks; growth was assessed by linear and spatial measurements of craniofacial regions.
Linear data disclosed shortening of the left nasal bone (P < .05) in groups 2 through 4. Groups 3 and 4 also had shortened left zygomatic arches and orbital diameters (P < .05). Euclidean distance matrix analysis showed significant restrictive shape alterations in groups 2 through 4 (P < .05). Significant contralateral shape alterations also were found in group 3.
Rigid plate fixation does not cause more severe growth disturbance than bony trauma. Use of rigid plate fixation after bony trauma does not seem to increase the restrictive effects of trauma on growth. Furthermore, removal of rigid plate fixation may not prevent growth disturbances and may induce further harmful trauma to the growing midface.
研究软组织操作、坚固微型钢板固定和多处截骨术对兔生长中的中面部的影响。
随机对照实验。
40只6周龄雄性新西兰白兔。
第1组，暴露左侧鼻额和颧弓中部区域并进行骨膜剥离；第2组，在左侧鼻额缝和颧弓中部进行截骨术；第3组，对截骨处进行坚固钢板固定；第4组，仅进行坚固钢板固定。动物在20周龄时处死；通过对头面部区域进行线性和空间测量来评估生长情况。
线性数据显示，第2组至第4组左侧鼻骨缩短（P < 0.05）。第3组和第4组左侧颧弓和眶径也缩短（P < 0.05）。欧几里得距离矩阵分析显示，第2组至第4组存在显著的限制性形态改变（P < 0.05）。第3组还发现了显著的对侧形态改变。
坚固钢板固定不会比骨创伤导致更严重的生长紊乱。骨创伤后使用坚固钢板固定似乎不会增加创伤对生长的限制作用。此外，去除坚固钢板固定可能无法预防生长紊乱，反而可能对生长中的中面部造成进一步的有害创伤。
