Roux H, D'Omezon Y, Lagier C, Thouveny F, Recordier A M
Rev Rhum Mal Osteoartic. 1976 Feb;43(2):113-6.
The authors report the results obtained from the treatment of 13 cases of myeloma by cyclic chemotherapy (melphalan) applied after cellular synchronization with vincristine. The clinical results (maximum 2 years after treatment) were good in 11 cases out of 13. The following laboratory values quickly returned to normal: sedimentation and calcaemia, but there was little change in the immunoglobulins.
作者报告了通过长春新碱进行细胞同步化后应用环磷酰胺(马法兰)对13例骨髓瘤患者进行治疗所获得的结果。临床结果(治疗后最长2年)显示,13例中有11例情况良好。以下实验室指标迅速恢复正常:血沉和血钙,但免疫球蛋白变化不大。