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产后抑郁症的病程及复发情况。诊断概念特异性的证据。

Course and recurrence of postnatal depression. Evidence for the specificity of the diagnostic concept.

作者信息

Cooper P J, Murray L

机构信息

Department of Psychology, University of Reading.

出版信息

Br J Psychiatry. 1995 Feb;166(2):191-5. doi: 10.1192/bjp.166.2.191.

Abstract

BACKGROUND

It is unclear whether the causative factors of non-psychotic postnatal depression are the same as those of depression at other times.

METHOD

The course and recurrence of postnatal depression was studied in two groups of primiparous women experiencing an index episode of postnatal depression: those for whom the mood disorder had arisen de novo (n = 34), and those for whom it was a recurrence of previous affective disturbance (n = 21). The mental state of these two groups, together with a psychiatrically well control group (n = 40), was studied for five years.

RESULTS

It was found that those for whom the index episode was a recurrence of depression were at raised risk of further non-postpartum episodes but not postpartum episodes, and that those for whom the index episode had arisen de novo were at raised risk for further episodes of postnatal depression but not for non-postpartum episodes.

CONCLUSION

These findings suggest a specific nosologic reference for the concept of postnatal depression.

摘要

背景

非精神病性产后抑郁症的致病因素是否与其他时期的抑郁症相同尚不清楚。

方法

对两组初产妇产后抑郁症首次发作的病程和复发情况进行了研究:一组是新发情绪障碍的产妇(n = 34),另一组是既往情感障碍复发的产妇(n = 21)。对这两组产妇以及一个精神状态良好的对照组(n = 40)进行了为期五年的研究。

结果

发现首次发作是抑郁症复发的产妇发生非产后发作的风险增加,但产后发作风险未增加;而首次发作是新发的产妇发生产后抑郁症再次发作的风险增加,但非产后发作风险未增加。

结论

这些发现提示产后抑郁症概念有特定的疾病分类依据。

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