多发性透明细胞棘皮瘤的成功冷冻治疗及概述
Successful cryotherapic treatment and overview of multiple clear cell acanthomas.
作者信息
Betti R, Bruscagin C, Inselvini E, Palvarini M, Crosti C
机构信息
Clinica Dermatologica IV, Università degli Studi di Milano, Ospedale S. Paolo, Italy.
出版信息
Dermatol Surg. 1995 Apr;21(4):342-4. doi: 10.1111/j.1524-4725.1995.tb00187.x.
BACKGROUND
Clear cell acanthoma (CCA) is a usually solitary benign epidermal-tumor. Multiple lesions are infrequently reported.
OBJECTIVE
A case of multiple eruptive CCA is reported in which a successful cryotherapic treatment was performed.
METHODS
A 59-year-old man with varicose veins and dry skin presented with 17 eruptive asymptomatic papulo-nodular lesions on both legs.
RESULTS
Two lesions were excised with a histologically confirmed diagnosis of CCA. Other lesions were treated with liquid nitrogen. All the lesions resolved with minimal residual scarring after three to four treatments.
CONCLUSIONS
Multiple CCA is a rare condition; fewer than 20 cases having been described. The presence of associated conditions like dry skin and varicose veins are discussed. Because of the tendency of persistence of the lesions, cryotherapic treatment may be a useful method of therapy.
背景
透明细胞棘皮瘤（CCA）是一种通常为单发的良性表皮肿瘤。多发损害的报道较为少见。
目的
报告1例多发性发疹性CCA病例，该病例接受了成功的冷冻治疗。
方法
一名59岁男性，有静脉曲张和皮肤干燥，双下肢出现17个无症状的发疹性丘疹结节性损害。
结果
切除2个损害，组织学确诊为CCA。其他损害采用液氮治疗。经过三到四次治疗后，所有损害均消退，仅留轻微瘢痕。
结论
多发性CCA是一种罕见疾病；描述的病例少于20例。文中讨论了皮肤干燥和静脉曲张等相关疾病的存在情况。由于损害有持续存在的倾向，冷冻治疗可能是一种有效的治疗方法。
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