Monari Paola, Farisoglio Camillo, Gualdi Giulio, Botali Giorgio, Ungari Marco, Calzavara-Pinton Piergiacomo
Department of Dermatology, University of Brescia, Brescia, Italy.
J Dermatol Case Rep. 2010 Nov 19;4(2):25-7. doi: 10.3315/jdcr.2010.1048.
Clear cell acanthoma is a rare solitary benign epidermal tumor of unknown etiology. The disease arises in the middle-age, with no sex predominance. It appears as a single reddish papule or papule-nodule and a peripheral scaling collarette is characteristic. Although solitary lesions are the rule, less than 30 cases of multiple Clear cell acanthoma have been described in the literature to date.
We report an unusual case of a healthy 74-year-old male with multiple clear cell acanthoma on the lower extremities treated successfully with cryotherapy.
Despite significant progress in treatment of clear cell acanthoma, cryotherapy, based on liquid nitrogen, remains an important alternative in treating multiple clear cell acanthomas.
透明细胞棘皮瘤是一种病因不明的罕见孤立性良性表皮肿瘤。该疾病好发于中年,无性别差异。表现为单个红色丘疹或丘疹结节,周围有鳞屑性领圈是其特征。虽然通常为孤立性病变,但迄今为止文献中报道的多发性透明细胞棘皮瘤病例不到30例。
我们报告了一例不寻常的病例,一名74岁健康男性下肢患有多发性透明细胞棘皮瘤,经冷冻治疗成功治愈。
尽管透明细胞棘皮瘤的治疗取得了显著进展,但基于液氮的冷冻治疗仍是治疗多发性透明细胞棘皮瘤的重要替代方法。