Trifonova N A, Ismail-Zade I A, Michelson V A
Cah Anesthesiol. 1994;42(5):577-81.
In children undergoing mesenterico-caval or distal spleno-renal shunting for extrahepatic portal hypertension, dobutamin (3-5 micrograms.kg-1.min-1 for 24 hr postoperatively) prevents right ventricle dysfunction and pulmonary hypertension resulting from suddenly increased blood return to the heart by the inferior vena cava, thus improving cardiac output and myocardial contractility. Twelve 1-15 yr children benefitted from this inotropic therapy without any adverse side effect.
在接受肠系膜-腔静脉分流术或远端脾肾分流术治疗肝外门静脉高压症的儿童中,多巴酚丁胺(术后24小时3 - 5微克·千克⁻¹·分钟⁻¹)可预防因下腔静脉回心血量突然增加导致的右心室功能障碍和肺动脉高压,从而改善心输出量和心肌收缩力。12名1至15岁的儿童受益于这种正性肌力治疗,且无任何不良反应。