Fedoruk L M, Bojm M A, Bugis S P
Department of Surgery, Royal Columbian Hospital, New Westminster, BC.
Can J Surg. 1995 Apr;38(2):173-7.
To determine the predictive value of fine-wire localization (FWL) biopsy.
A chart review.
The Royal Columbian Hospital, New Westminster, BC.
Two hundred and thirty-five women who underwent 239 biopsies for abnormal mammographic findings between Jan. 1, 1991, and Dec. 31, 1992. The average age was 58 years (range from 33 to 83 years).
FWL biopsy.
Positive findings of cancer on FWL biopsy.
Mammographic findings were as follows: a mass only in 98 cases (41.0%), microcalcification in 90 (37.7%), a spiculated mass in 20 (7.5%), an ill-defined density in 18 (8.4%) and a mass with microcalcification in 13 (5.4%). Malignant lesions were found in 97 (40.6%) of 239 biopsies. These included 55 infiltrating ductal carcinomas, 31 in-situ carcinomas, 7 infiltrating lobular carcinomas and 4 miscellaneous carcinomas. Spiculated masses were associated with malignancy in 18 (90%) of the 20 biopsies. Also, 41 (42%) of the 98 masses and 30 (33%) of the 90 microcalcifications were malignant. Only 4 (31%) of the 13 masses with associated microcalcification and 4 (22%) of the 18 ill-defined densities were malignant.
The 40.6% rate of positive findings supports the use of FWL biopsy as a valuable tool in the diagnosis of nonpalpable breast cancers.
确定细针定位（FWL）活检的预测价值。
病历回顾。
不列颠哥伦比亚省新威斯敏斯特市的皇家哥伦比亚医院。
1991年1月1日至1992年12月31日期间因乳腺X线摄影异常接受239次活检的235名女性。平均年龄为58岁（范围33至83岁）。
FWL活检。
FWL活检的癌症阳性结果。
乳腺X线摄影结果如下：仅发现肿块98例（41.0%），微钙化90例（37.7%），毛刺状肿块20例（7.5%），边界不清的密度影18例（8.4%），伴有微钙化的肿块13例（5.4%）。239次活检中有97例（40.6%）发现恶性病变。其中包括55例浸润性导管癌、31例原位癌、7例浸润性小叶癌和4例其他类型癌。20例活检中有18例（90%）毛刺状肿块与恶性肿瘤相关。此外，98个肿块中有41个（42%）、90个微钙化中有30个（33%）为恶性。13个伴有微钙化的肿块中只有4个（31%）、18个边界不清的密度影中有4个（22%）为恶性。
40.6%的阳性率支持将FWL活检作为诊断不可触及乳腺癌的一种有价值的工具。
