Kita K, Hirayama K, Tokumaru Y, Kijima M
Department of Neurology, Chiba University School of Medicine.
Rinsho Shinkeigaku. 1994 Nov;34(11):1089-92.
Chiromegaly, localized hypertrophy of a hand, is known to be a rare but pathognomonic trophic disturbance in syringomyelia. We recently reported that the sympathetic hyperfunction was associated with chiromegaly. This time we carried out radiological studies of hand bones in 4 patients with syringomyelic chiromegaly. In simple roentogenography, enlargement and enhanced shadows of hand bones were recognized in the chiromegalic side. Radiographic measurements showed metacarpophalangeal length and width were increased by 1.7% and 8.8% respectively compared to the normal side, and metacarpal index was decreased significantly in the chiromegalic side. In X-ray photodensitometry (MD/MS method) of the second metacarpal bones, bone density was increased by 10.6% compared to the normal side. These results suggested that bone hypertrophy was associated with chiromegaly in patient with syringomyelia. Trophic disturbance may exert some influence on the bone tissue.
手部局限性肥大即巨手症，是脊髓空洞症中一种罕见但具有诊断意义的营养障碍。我们最近报道过交感神经功能亢进与巨手症有关。此次我们对4例脊髓空洞症所致巨手症患者的手部骨骼进行了放射学研究。在普通X线摄影中，患侧手部骨骼出现增大及阴影增强。放射学测量显示，与健侧相比，患侧掌指骨长度和宽度分别增加了1.7%和8.8%，掌骨指数在患侧显著降低。在第二掌骨的X线光密度测定法（MD/MS法）中，骨密度较健侧增加了10.6%。这些结果提示，脊髓空洞症患者的骨肥大与巨手症有关。营养障碍可能会对骨组织产生一定影响。
