Takeda M, Okuda B, Tachibana H, Sugita M
Fifth Department of Internal Medicine, Hyogo College of Medicine.
Rinsho Shinkeigaku. 1994 Nov;34(11):1168-70.
We report a 65-year-old female who have suffered from progressive gait disturbance for 3 years, followed by disorientation and forgetfulness. Neurological examination revealed dementia, constructional disability, limb kinetic apraxia, supranuclear gaze palsy, especially on downward gaze, symmetrical muscle rigidity and bradykinesia. Involuntary movements were undetectable. Brain MRI showed significant brain atrophy in the left fronto-parietal lobe. The three-dimensional surface display with 131I-IMP demonstrated decreased cerebral blood flow in the left frontoparietal cortex. The diagnosis of this case is discussed with regard to either progressive supranuclear palsy or corticobasal degeneration or both.
我们报告一例65岁女性，她有进行性步态障碍3年，随后出现定向障碍和健忘。神经系统检查发现痴呆、结构性失用、肢体运动性失用、核上性凝视麻痹，尤其是向下凝视时、对称性肌肉强直和运动迟缓。未检测到不自主运动。脑部MRI显示左额顶叶有明显脑萎缩。131I-IMP三维表面显像显示左额顶叶皮质脑血流量减少。对该病例的诊断就进行性核上性麻痹或皮质基底节变性或两者进行了讨论。
