Jabbour N, Reyes J, Zajko A, Nour B, Tzakis A G, Starzl T E, Van Thiel D H
Department of Surgery, University of Pittsburgh Medical Center, Pennsylvania 15213, USA.
Dig Dis Sci. 1995 May;40(5):1041-4. doi: 10.1007/BF02064196.
Although liver biopsy is a very useful procedure used frequently in the diagnosis and management of liver dysfunction occurring after orthotopic liver transplantation, complications can occur with its use. An unusual complication of arterioportal fistula is reported here. Based upon this small series of an unusual event and the knowledge that the posttransplant liver may be more hypervascular than prior to OLTx and that it is uniquely susceptible to hepatic infarction and abscess formation, any attempt at fistula closure should be considered carefully prior to initiating the therapy (15). Unless a serious complication occurs [such as a transient biliary obstruction due to hemobilia as occurred in case 2, portal hypertension as also occurred in case 2, or systemic sepsis or other symptoms develop related directly to the fistula], simple observation may be the best choice of action. Should therapy be required, hepatic arterial embolization should be reserved for adults with intrahepatic fistulas. Primary surgical closure of intrahepatic fistula should be reserved for cases of extrahepatic fistula.
尽管肝活检是原位肝移植后肝功能障碍的诊断和管理中经常使用的非常有用的程序,但其使用可能会出现并发症。本文报告了一例罕见的动脉门静脉瘘并发症。基于这一小系列的不寻常事件,以及移植后肝脏可能比肝移植前血管更丰富,且特别易发生肝梗死和脓肿形成的认识,在开始治疗前应仔细考虑任何瘘管闭合的尝试(15)。除非发生严重并发症[如病例2中因胆道出血导致的短暂性胆管梗阻、病例2中也出现的门静脉高压,或直接与瘘管相关的全身感染或其他症状],单纯观察可能是最佳行动选择。如果需要治疗,肝动脉栓塞应仅用于患有肝内瘘的成人。肝内瘘的一期手术闭合应仅用于肝外瘘的病例。