Jeffers M, Cowan C, Lunan C B
Department of Pathology, Royal Infirmary, Glasgow.
J Clin Pathol. 1995 Mar;48(3):278-80. doi: 10.1136/jcp.48.3.278.
Degenerative changes are encountered relatively frequently in uterine leiomyomas. Morphologic changes within leiomyomas, particularly necrosis and alterations in cellularity, have been described following treatment with gonadotrophin releasing hormone analogue, but the effects of this form of treatment on the morphology of the normal myometrium are less well documented. A case is reported of a 42 year old woman with a history of menorrhagia in whom a combination of degenerative and iatrogenic changes resulted in a histological appearance resembling diffuse leiomyomatosis.
子宫平滑肌瘤中相对常见退行性改变。用促性腺激素释放激素类似物治疗后，已描述了平滑肌瘤内的形态学变化，尤其是坏死和细胞密度改变，但这种治疗方式对正常子宫肌层形态的影响记录较少。本文报告一例42岁有月经过多病史的女性，其退行性和医源性改变共同导致了类似弥漫性平滑肌瘤病的组织学表现。
