Berardi J C, Colau J C, Engelmann P, Botto J N, Vige P, Robichez B
C.H. F.-Quesnay, Mantes-La-Jolie.
J Gynecol Obstet Biol Reprod (Paris). 1995;24(1):69-73.
To determine the relationship between bacterial colonization of the amniotic fluid sampled by amniocentesis and premature rupture of the membranes.
A prospective multicentric study conducted over a one year period in 6 maternity wards in the suburban area of Paris. Thirty-six women with premature rupture of the membranes were studied.
There were 11 patients (30%) with contaminated fluid at the first amniocentesis. Twenty-five patients had sterile fluid. In 7 patients with prolonged rupture for more than one week, repeated amniocentesis. Twenty-five patients had sterile fluid. In 7 patients with prolonged rupture for more than one week, repeated amniocenteses were used to follow bacterial colonization. In one patient, Proteus mirabilis in the amniotic fluid was eradicated by adapted antibiotic therapy. In patients with sterile amniotic fluid, there was no secondary colonization. In the 11 cases with colonized liquid, the vaginal swab could only be considered as positive in 4 cases. Amniocentesis was able to discover 7 bacterial colonizations of the amniotic fluid in patients with an indeterminant vaginal swab. Likewise, C-reactive protein levels were raised only in 26% of the cases with a colonized amniotic fluid.
确定羊膜腔穿刺采集的羊水细菌定植与胎膜早破之间的关系。
在巴黎郊区的6个产科病房进行了为期一年的前瞻性多中心研究。对36例胎膜早破的女性进行了研究。
首次羊膜腔穿刺时，有11例患者（30%）羊水被污染。25例患者羊水无菌。7例胎膜破裂时间延长超过一周的患者进行了重复羊膜腔穿刺。25例患者羊水无菌。7例胎膜破裂时间延长超过一周的患者，采用重复羊膜腔穿刺来监测细菌定植情况。1例患者羊水中的奇异变形杆菌通过适当的抗生素治疗被清除。羊水无菌的患者没有继发定植。在11例羊水定植的病例中，阴道拭子仅在4例中被视为阳性。羊膜腔穿刺能够在阴道拭子结果不确定的患者中发现7例羊水细菌定植。同样，羊水定植的病例中只有26%的患者C反应蛋白水平升高。
