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哺乳动物钠氢交换体的结构/功能研究——最新进展

Structure/function studies of mammalian Na-H exchangers--an update.

作者信息

Yun C H, Tse C M, Nath S, Levine S L, Donowitz M

机构信息

Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

出版信息

J Physiol. 1995 Jan;482(P):1S-6S. doi: 10.1113/jphysiol.1995.sp020558.

Abstract

Four mammalian Na+/H+ exchangers have recently been cloned. Despite the structural similarity, these Na+/H+ exchanger isoforms differ in kinetic characteristics and their response to external stimuli. The present review deals with the recent developments in their functional characterization and their short-term regulation.

摘要

最近已克隆出四种哺乳动物的钠/氢交换体。尽管结构相似,但这些钠/氢交换体同工型在动力学特性及其对外界刺激的反应方面存在差异。本综述涉及它们功能特性和短期调节方面的最新进展。

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