Yun C H, Tse C M, Nath S, Levine S L, Donowitz M
Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
J Physiol. 1995 Jan;482(P):1S-6S. doi: 10.1113/jphysiol.1995.sp020558.
Four mammalian Na+/H+ exchangers have recently been cloned. Despite the structural similarity, these Na+/H+ exchanger isoforms differ in kinetic characteristics and their response to external stimuli. The present review deals with the recent developments in their functional characterization and their short-term regulation.
最近已克隆出四种哺乳动物的钠/氢交换体。尽管结构相似,但这些钠/氢交换体同工型在动力学特性及其对外界刺激的反应方面存在差异。本综述涉及它们功能特性和短期调节方面的最新进展。