Kageyama T
Department of Cellular and Molecular Biology, Kyoto University, Aichi, Japan.
J Med Primatol. 1994 Sep;23(7):375-81. doi: 10.1111/j.1600-0684.1994.tb00123.x.
Five pepsinogens were purified from the gastric mucosa of eight species of Asian macaques. The chromatographic behavior of each pepsinogen was essentially the same but differed from human and other mammalian pepsinogens. The major pepsinogen in each species was pepsinogen A-1, accounting for 29-48% of the total. Amino acid compositions and some enzymatic properties of derived pepsins were similar for the various monkey species. This high degree of similarity confirms that these species are closely related to one another.
从八种亚洲猕猴的胃黏膜中纯化出了五种胃蛋白酶原。每种胃蛋白酶原的色谱行为基本相同，但与人类和其他哺乳动物的胃蛋白酶原不同。每个物种中的主要胃蛋白酶原是胃蛋白酶原A-1，占总量的29%-48%。各种猴类衍生胃蛋白酶的氨基酸组成和一些酶学性质相似。这种高度的相似性证实了这些物种彼此之间密切相关。
