Aguirre V, Tagle R, Rosenberg H, Jacobelli S
Departamento de Reumatología e Inmunología Clínica, Escuela de Medicina, P Universidad Católica de Chile, Santiago de Chile.
Rev Med Chil. 1994 Jul;122(7):807-11.
Pregnancy in patients with systemic sclerosis may predispose to a fast progression of the disease. We report a woman with systemic sclerosis and multiple visceral involvement that during the third trimester of pregnancy developed a respiratory failure caused by interstitial fibrosis complicated with alveolar hemorrhage, bronchopneumonia and respiratory distress syndrome and a renal failure. On admission, she was subjected to a cesarean section, delivering a 1205 g newborn. In spite of intensive care support, the multisystemic failure became unmanageable and the patient died 15 days after admission. Literature review, although sometimes controversial, indicates that pregnancy is a situation with a definitive death risk for patients with systemic sclerosis, that requires a close follow up.
系统性硬化症患者怀孕可能会使疾病快速进展。我们报告了一名患有系统性硬化症且有多个内脏受累的女性，她在妊娠晚期出现呼吸衰竭，病因是间质性纤维化并发肺泡出血、支气管肺炎和呼吸窘迫综合征，同时还出现了肾衰竭。入院时，她接受了剖宫产手术，产下一名体重1205克的新生儿。尽管给予了重症监护支持，但多系统功能衰竭仍无法控制，患者在入院15天后死亡。文献综述表明，尽管有时存在争议，但怀孕对于系统性硬化症患者来说是一种明确存在死亡风险的情况，需要密切随访。
