[Morphological changes in the kidneys in refluxogenic nephropathy in patients with congenital and acquired vesicoureteral reflux].

Current views of foreign investigators on refluxogenic nephropathy rest on the results of pig experiments. The authors studied human material: kidneys of children who died of pyelonephritis caused by vesicoureteral reflux. Electron-microscopic and other morphological examinations of the kidney pelvic wall provided evidence for a distinct difference in relevant morphological structures observed in congenital versus acquired reflux. Congenital vesicoureteral reflux displays a specific morphological picture suggesting congenital refluxogenic nephropathy, whereas acquired reflux produces a typical picture of ascending pyelonephritis.