Sheu B S, Lin C Y, Chen K W, Chi C H, Chou N H, Lin X Z
Department of Internal Medicine, National Cheng Kung University Hospital, Tainan, Taiwan.
Am J Gastroenterol. 1995 May;90(5):833-5.
Chlormezanone is a widely prescribed muscle relaxant (1-3) whose pharmacology is well known (4-6), but the clinical effect of overdose still remains relatively obscure (1, 7, 8). We here report a recent case of a patient who had severe liver function impairment and other associated findings typical of chlormezanone overdose. The ingested dose (at least 12 g) is much larger than those of previous record (1, 2, 7, 8); thus, her critical presentation deserves to be reviewed.
氯美扎酮是一种广泛应用的肌肉松弛剂(1 - 3),其药理学特性已为人熟知(4 - 6),但过量服用的临床效果仍相对不明(1, 7, 8)。我们在此报告近期一例患者,该患者出现严重肝功能损害以及其他氯美扎酮过量典型的相关表现。摄入剂量(至少12克)远高于既往记录(1, 2, 7, 8);因此,她的危急情况值得回顾。