Makino H, Kumagai I, Hironaka K, Ota K, Shikata K, Ota Z
Third Department of Internal Medicine, Okayama University Medical School, Japan.
Am J Nephrol. 1995;15(2):168-71. doi: 10.1159/000168825.
Hematuria in patients with glomerulonephritis seems to result from the passage of red blood cells through anatomical gaps in the glomerular basement membrane. However, such morphological evidence has rarely been demonstrated. A patient with mixed connective tissue disease associated with membranous glomerulonephritis is described in whom the renal biopsy specimen showed an escape of red blood cells through a gap in the basement membrane. These findings support the morphological basis of hematuria in glomerulonephritis.
肾小球肾炎患者的血尿似乎是由于红细胞通过肾小球基底膜的解剖学间隙所致。然而,这种形态学证据很少得到证实。本文描述了一名患有与膜性肾小球肾炎相关的混合性结缔组织病的患者,其肾活检标本显示红细胞通过基底膜的间隙逸出。这些发现支持了肾小球肾炎血尿的形态学基础。