Translation in vivo of 5' untranslated-region splice variants of human surfactant protein-A.
作者信息
Karinch A M, Floros J
机构信息
Department of Cellular and Molecular Physiology, Pennsylvania State University, College of Medicine, Hershey 17033, USA.
出版信息
Biochem J. 1995 Apr 15;307 ( Pt 2)(Pt 2):327-30. doi: 10.1042/bj3070327.
Abstract
Transcripts of human SP-A genes, SP-A1 and SP-A2, undergo alternative splicing of 5' untranslated-region exons. We reverse-transcribed and amplified free cytoplasmic and polysome-bound RNA and showed that (a) all splice variants of both genes are translated in vivo, (b) the relative translatability of splice variants can differ among individuals, and (c) the relative levels of different SP-A splice variants differ among individuals.
摘要
Zotero 插件