一些具有抗菌活性的新型1,3,4-恶二唑啉-2-硫酮衍生物的合成
Synthesis of some new 1,3,4-oxadiazoline-2 thione derivatives with antibacterial activity.
作者信息
Mashaly M, Khodeir M N, Hanna M, El-Shafei H
机构信息
Department of Chemistry, Faculty of Science (Damietta), Mansoura University, Egypt.
出版信息
Boll Chim Farm. 1995 Jan;134(1):28-33.
PMID:7734124
Abstract
Three new 5-[(1-benzoylamino)styren-1-yl]-1,3,4-oxadiazoline-2- thiones and nine of their Mannich bases with some primary and secondary amines and three N-hydroxymethyl derivatives are synthesized. Some of the new derivatives were active against the bacteria Escherichia coli.
摘要
合成了三种新型的5-[(1-苯甲酰氨基)苯乙烯-1-基]-1,3,4-恶二唑啉-2-硫酮及其九个与一些伯胺和仲胺形成的曼尼希碱以及三种N-羟甲基衍生物。部分新衍生物对大肠杆菌具有活性。
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