Evidence of clonality in a child with haemophagocytic lymphohistiocytosis.
作者信息
Owen G, Webb D K
机构信息
Department of Paediatric Haematology and Oncology, Llandough Hospital, Penarth, South Glamorgan.
出版信息
Br J Haematol. 1995 Mar;89(3):681-2. doi: 10.1111/j.1365-2141.1995.tb08391.x.
Abstract
DNA from the bone marrow of a child with haemophagocytic lymphohistiocytosis was examined by polymerase chain reaction for evidence of rearrangement of the T-cell receptor delta chain gene. Evidence of clonal rearrangement was detected, supporting a role for abnormalities of T-cell function in the pathogenesis of this disorder.
摘要
Zotero 插件