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超声导致的细胞失活

Cell inactivation by ultrasound.

作者信息

Dakubu S

出版信息

Biotechnol Bioeng. 1976 Apr;18(4):465-71. doi: 10.1002/bit.260180403.

DOI:10.1002/bit.260180403
PMID:773447
Abstract

Cell survival curves have been obtained for Escherichia coli B (E. coli B) after the sonication of suspensions of the bacteria with continuous wave ultrasound at a fixed frequency of 2 MHZ between peak intensities of 8.7 and 2.25 W cm-2. It was found that under suitable conditions the survival curves were reproducible and it also was found that there was a clear relationship between the rate of inactivation and the peak acoustic intensity of the ultrasound. There appeared to be a lower threshold of peak intensity below which no inactivation was observed.

摘要

在用频率固定为2兆赫兹的连续波超声对大肠杆菌B(E. coli B)菌悬液进行超声处理后,获得了其细胞存活曲线,超声峰值强度介于8.7和2.25瓦/平方厘米之间。结果发现,在合适条件下,存活曲线具有可重复性,并且还发现失活速率与超声的峰值声强之间存在明确关系。似乎存在一个峰值强度下限,低于此下限未观察到失活现象。

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Cell inactivation by ultrasound.超声导致的细胞失活
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