Barreda Costa C
Universidad Nacional Mayor de San Marcos.
Rev Gastroenterol Peru. 1995 Jan-Apr;15(1):21-5.
A prospective study concerning colorectal polyps in symptomatic patients was held at Lima, Perú, an area considered of low incidence for colorectal neoplasia. In 137 patients, 272 polyps were resected by colonoscopic polypectomy or surgery. 55.9% were adenomas, 40.4% non neoplastic polyps and 3.7% polypoid carcinomas. The distribution of polyps, and the incidence of dysplasia and malignant changes in the adenomas, were similar of that reported in areas with high incidence of colorectal cancer. A high proportion of patients with adenomas (21.4% had a synchronous advanced carcinoma, specially if there were multiple adenomas. The figure was lower in patients with only non neoplastic polyps (7.5%). There were no cases of "de novo" carcinoma. This evidence suggest that adenomas play an essential role in colorectal cancer histogenesis, even in areas of low incidence of this neoplasia.
在秘鲁利马进行了一项关于有症状患者大肠息肉的前瞻性研究，该地区被认为是大肠肿瘤低发区。137例患者中，通过结肠镜息肉切除术或手术切除了272枚息肉。其中55.9%为腺瘤，40.4%为非肿瘤性息肉，3.7%为息肉样癌。息肉的分布以及腺瘤中发育异常和恶性变化的发生率与结直肠癌高发地区报道的相似。高比例的腺瘤患者（21.4%有同步进展期癌，尤其是存在多个腺瘤时。仅有非肿瘤性息肉的患者这一比例较低（7.5%）。没有“新发”癌的病例。这一证据表明，腺瘤在结直肠癌的组织发生中起重要作用，即使在该肿瘤低发地区也是如此。
