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[急性和持续性腹泻患儿肠道微生物群的研究]

[Study of intestinal microflora in children with acute and persistent diarrhea].

作者信息

Garcia Cristia Y, Fragoso Arbelo T, Valdes-Dapena Vivanco M, Sagaro Gonzales E, Gorrin Castellanos N

机构信息

Instituto de Ciencias Médicas de la Habana.

出版信息

Rev Gastroenterol Peru. 1995 Jan-Apr;15(1):35-41.

PMID:7734709
Abstract

The etiology and pathogenesis of persistent diarrhoea is usually multifactorial and sometimes can not be identified. It is necessary to define if an alteration of the enteric microflora is a risk factor that influence the duration of the diarrhoea. 30 infants with acute diarrhoea and 30 with persistent diarrhoea were studied. A sample of duodenal content was taken by a double-lumen tube and processed microbiologically in search for enteric microorganisms, anaerobic and Candida. These results were correlated with the nutritional status, the previous use of Metronidazole and the results of the stool culture. The presence of bacterial overgrowth and the identification of the duodenal microflora is an important factor for the persistence of the diarrhoea. There was a quantitative and qualitative alteration of the duodenal flora in both groups of patients.

摘要

持续性腹泻的病因和发病机制通常是多因素的,有时难以明确。确定肠道微生物群的改变是否是影响腹泻持续时间的危险因素很有必要。研究了30例急性腹泻婴儿和30例持续性腹泻婴儿。通过双腔管采集十二指肠内容物样本,并进行微生物学处理以寻找肠道微生物、厌氧菌和念珠菌。这些结果与营养状况、先前使用甲硝唑的情况以及粪便培养结果相关。细菌过度生长的存在和十二指肠微生物群的鉴定是腹泻持续存在的重要因素。两组患者的十二指肠菌群均存在定量和定性改变。

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